Article
Expression of phenotype- and proliferation-related genes in rat aortic smooth muscle cells in primary culture.
Cardiovascular research - 1 May 1997
Hultgårdh-Nilsson A, Lövdahl C, Blomgren K, Kallin B, Thyberg J
Abstract excerpt
OBJECTIVES: After endothelial injury, smooth muscle cells (SMCs) in the arterial media are modified from a contractile to a sympathetic phenotype. This process includes a prominent structural reorganization and makes the cells able to migrate into the intima, divide, and secrete extracellular matrix components. A similar change occurs in culture and then in vitro system has been established as a useful model in...
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