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Article

Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells.

Kidney international - 1 May 1993

Marx M, Daniel T O, Kashgarian M, Madri J A

Abstract excerpt

The aim of this study was to test the hypothesis that changes in the extracellular matrix environment regulate rat mesangial cell growth by modulation of the expression of both PDGF-receptor alpha- and beta-subunits. We investigated the mitogenic effects of the PDGF isoforms AA, AB and BB in conventional two-dimensional (2D) culture on laminin, fibronectin, type I, IV and V collagen and in the different spatial...

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Source

Identifiers

PMID: 8510381
DOI: 10.1038/ki.1993.145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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