Article
ANG II receptor expression and function during phenotypic modulation of rat aortic smooth muscle cells.
The American journal of physiology - 1 Feb 1994
Corriu C, André P, Schott C, Michel M, Stoclet J C
Abstract excerpt
Angiotensin II (ANG II) receptors were investigated in primary cultured rat aortic smooth muscle cells (SMC) that expressed either a proliferative phenotype (during the growth phase) or a contractile phenotype (at postconfluence). For each phenotype, alpha-smooth muscle actin expression, 125I-labeled ANG II specific binding, D-myo-inositol 1,4,5-triphosphate [Ins(1,4,5)P3] production, and ANG II-mediated...
Topics
- Actins
- Angiotensin I
- Angiotensin III
- Animals
- Aorta, Thoracic
- Biphenyl Compounds
- Calcium
- Cattle
- Cell Division
- Cells, Cultured
- Endothelium, Vascular
- Imidazoles