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HDV-like self-cleaving ribozymes

1 Sept 2011

Abstract excerpt

HDV ribozymes catalyze their own scission from the transcript during rolling circle replication of the hepatitis delta virus. In vitro selection of self-cleaving ribozymes from a human genomic library revealed an HDV-like ribozyme in the second intron of the human CPEB3 gene and recent results suggest that this RNA affects episodic memory performance. Bioinformatic searches based on the secondary structure of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21734469
DOI: 10.4161/rna.8.5.16226

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