Article
Complex pedigrees in the sequencing era: to track transmissions or decorrelate?
Genetic epidemiology - 1 Sept 2014
Li Dalin, Zhou Jin, Thomas Duncan C, Fardo David W
Abstract excerpt
Next-generation sequencing (NGS) studies are becoming commonplace, and the NGS field is continuing to develop rapidly. Analytic methods aimed at testing for the various roles that genetic susceptibility plays in disease are also rapidly being developed and optimized. Studies that incorporate large, complex pedigrees are of particular importance because they provide detailed information about inheritance patterns...
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