Article
Detecting Pedigree Relationship Errors.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Sun Lei
Abstract excerpt
Pedigree relationship errors often occur in family data collected for genetic studies, and unidentified errors can lead to either increased false positives or decreased power in both linkage and association analyses. Here, we review several allele sharing as well as likelihood-based statistics that were proposed to efficiently extract genealogical information from available genome-wide marker data, and the...
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