Article
Inferring haplotypes and parental genotypes in larger full sib-ships and other pedigrees with missing or erroneous genotype data.
BMC genetics - 10 Oct 2012
Nettelblad Carl
Abstract excerpt
BACKGROUND: In many contexts, pedigrees for individuals are known even though not all individuals have been fully genotyped. In one extreme case, the genotypes for a set of full siblings are known, with no knowledge of parental genotypes. We propose a method for inferring phased haplotypes and genotypes for all individuals, even those with missing data, in such pedigrees, allowing a multitude of classic and...
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