Article
Genetic analysis of iron-deficiency effects on the mouse spleen.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2011
Gibson Jennifer N, Jellen Leslie C, Unger Erica L, Morahan Grant, Mehta Munish, Earley Christopher J, Allen Richard P, Lu Lu, Jones Byron C
Abstract excerpt
Iron homeostasis is crucial to many biological functions in nearly all organisms, with roles ranging from oxygen transport to immune function. Disruption of iron homeostasis may result in iron overload or iron deficiency. Iron deficiency may have severe consequences, including anemia or changes in immune or neurotransmitter systems. Here we report on the variability of phenotypic iron tissue loss and splenomegaly...
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