Article
Systems genetic analysis of the effects of iron deficiency in mouse brain.
Neurogenetics - 1 May 2012
Jellen Leslie C, Unger Erica L, Lu Lu, Williams Robert W, Rousseau Sarah, Wang Xusheng, Earley Christopher J, Allen Richard P, Miles Michael F, Jones Byron C
Abstract excerpt
Iron regulation in the brain is both necessary and highly complex. Too little or too much iron can compromise neurological function, yet we still do not know all of the regulatory processes. In our research, we seek to identify genes and gene networks underlying individual differences in brain iron regulation. To this end, we fed mice from 20+ inbred strains a diet low in iron from weaning to 4 months of age. At...
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