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Article

Identification of quantitative trait loci for diabetic nephropathy in KK-Ay/Ta mice.

Journal of nephrology - 1 Jan 2000

Aoki Tatsuya, Kaneko Shigeru, Tanimoto Mitsuo, Gohda Tomohito, Hagiwara Shinji, Murakoshi Maki, Ishikawa Yuji, Furukawa Masako, Funabiki Kazuhiko, Horikoshi Satoshi, Tomino Yasuhiko

Abstract excerpt

BACKGROUND: The pathogenesis and development of human diabetic nephropathy involves genetic factors. Since human diabetic nephropathy is a heterogeneous disorder, identification of responsible gene loci is difficult. We studied candidate gene loci for diabetic nephropathy, using quantitative trait locus (QTL) analysis of a spontaneous animal model for diabetic nephropathy: KK-Ay/Ta × normal BALB/cA F2 intercross...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21725918
DOI: 10.5301/JN.2011.8433

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ACR

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