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Article

FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuria.

American journal of physiology. Renal physiology - 1 Sept 2010

Xu Jianxiang, Huang Yun, Li Fenge, Zheng Shirong, Epstein Paul N

Abstract excerpt

OVE26 (OVE) diabetic mice on the inbred strain FVB are a valuable model of diabetic nephropathy that excretes the highest amount of urine albumin of all diabetic mouse models. Crossing of OVE mice to C57BL6 or DBA2 mice reduced albuminuria 17-fold in F1 diabetic offspring without reducing diabetes. When comparing renal histology of OVE mice on the FVB background to F1 C57BL6 crosses, we found that the F1 kidneys...

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Identifiers

PMID: 20610531
DOI: 10.1152/ajprenal.00018.2010
PMCID: PMC2944296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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