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Article

A major X-linked locus affects kidney function in mice.

Molecular genetics and genomics : MGG - 1 Dec 2012

Leduc Magalie S, Savage Holly S, Stearns Timothy M, Cario Clinton L, Walsh Kenneth A, Paigen Beverly, Berndt Annerose

Abstract excerpt

Chronic kidney disease is a common disease with increasing prevalence in the western population. One common reason for chronic kidney failure is diabetic nephropathy. Diabetic nephropathy and hyperglycemia are characteristics of the mouse inbred strain KK/HlJ, which is predominantly used as a model for metabolic syndrome due to its inherited glucose intolerance and insulin resistance. We used KK/HlJ, an...

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Identifiers

PMID: 23011808
DOI: 10.1007/s00438-012-0720-x
PMCID: PMC3508201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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