Genetic analysis of non-insulin-dependent diabetes mellitus in KK and KK-Ay mice.

doi:10.1530/eje.0.1390654

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Article

Genetic analysis of non-insulin-dependent diabetes mellitus in KK and KK-Ay mice.

European journal of endocrinology - 1 Dec 1998

Suto J, Matsuura S, Imamura K, Yamanaka H, Sekikawa K

Abstract excerpt

The KK mouse is considered suitable as a polygenic model for human non-insulin-dependent diabetes mellitus. To identify the quantitative trait loci (QTLs) responsible for hyperglycemia and impaired glucose tolerance in KK mice, linkage analysis using 97 microsatellite markers was carried out in a...

Topics

Alleles
Analysis of Variance
Animals
Diabetes Mellitus, Type 2
Disease Models, Animal
Female
Genetic Linkage
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains

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