Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.

Kidney international - 1 Jun 2012

Yu Ling, Su Yan, Paueksakon Paisit, Cheng Huifang, Chen Xiwu, Wang Hongtao, Harris Raymond C, Zent Roy, Pozzi Ambra

Abstract excerpt

Animal models that mimic human diabetic nephropathy are useful to identify key factors in pathogenesis of this disease, as well as the development of new therapies. Several mouse models of diabetes have features of human diabetic nephropathy, yet none of these completely fulfill the Animal Models of Diabetes Complications Consortium criteria and completely reproduce pathological and functional features of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Diabetic Nephropathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibrosis

Share to Glomerular Filtration Rate

Share to Glomerulonephritis

Share to Kidney Glomerulus

Share to Mice, Mutant Strains

Share to Sclerosis

Source

Open in PubMed Open full text

Identifiers

PMID: 22297672
DOI: 10.1038/ki.2011.474
PMCID: PMC3345314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrin α1/Akita double-knockout mice on a Balb/c background develop advanced features of human diabetic nephropathy.PMID 22297672Read ↗

Assessment of diabetic nephropathy in the Akita mouse.Semantic proximity Read ↗

Influence of genetic background on albuminuria and kidney injury in Ins2(+/C96Y) (Akita) mice.Semantic proximity Read ↗

Diabetic nephropathy in a nonobese mouse model of type 2 diabetes mellitus.Semantic proximity Read ↗

Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.Semantic proximity Read ↗

Impact of genetic background on nephropathy in diabetic miceSemantic proximity Read ↗

Generating double knockout mice to model genetic intervention for diabetic cardiomyopathy in humans.Semantic proximity Read ↗

Mouse Models of Diabetic NephropathySemantic proximity Read ↗

Mouse models of diabetic nephropathy.Semantic proximity Read ↗

Identification of quantitative trait loci for diabetic nephropathy in KK-Ay/Ta mice.Semantic proximity Read ↗

Null mutations at the p66 and bradykinin 2 receptor loci induce divergent phenotypes in the diabetic kidney.Semantic proximity Read ↗

Retinal Angiogenesis in the Ins2<sup>Akita</sup>Mouse Model of Diabetic RetinopathySemantic proximity Read ↗

Inflammation and Immunity Pathways Regulate Genetic Susceptibility to Diabetic Nephropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.