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Article

Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease.

Journal of gastroenterology - 1 Sept 2011

Miyoshi Jun, Yajima Tomoharu, Okamoto Susumu, Matsuoka Katsuyoshi, Inoue Nagamu, Hisamatsu Tadakazu, Shimamura Katsuyoshi, Nakazawa Atsushi, Kanai Takanori, Ogata Haruhiko, Iwao Yasushi, Mukai Makio, Hibi Toshifumi

Abstract excerpt

BACKGROUND: Host-intestinal microbial interaction plays an important role in the pathogenesis of inflammatory bowel diseases (IBDs). The surface molecules of the intestinal epithelium act as receptors for bacterial adhesion and regulate the intestinal bacteria. Some known receptors are the mucosal blood type antigens, which are regulated by the fucosyltransferase2 (FUT2) gene, and individuals who express these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21725903
DOI: 10.1007/s00535-011-0425-7

Genes

FUT2

Provenance

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Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease.PMID 21725903Read ↗

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