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Fucosyltransferase 2: A Genetic Risk Factor for Intestinal Diseases

18 Jul 2022

Abstract excerpt

The fucosyltransferase 2 gene ( FUT2 ) mediates the synthesis of histoblood group antigens (HBGA) that occur in vivo from multiple organs, particularly on the surface of intestinal epithelial cells and body fluids. To date, many studies have demonstrated that the interaction of HBGA with the host microbiota is the cause of pathogenesis of intestinal diseases, making FUT2 non-secretor a risk factor for...

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PMID: 35923409
DOI: 10.3389/fmicb.2022.940196

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