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Article

ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior.

Journal of Crohn's & colitis - 1 Jun 2014

Forni Diego, Cleynen Isabelle, Ferrante Marc, Cassinotti Andrea, Cagliani Rachele, Ardizzone Sandro, Vermeire Severine, Fichera Maria, Lombardini Marta, Maconi Giovanni, de Franchis Roberto, Asselta Rosanna, Biasin Mara, Clerici Mario, Sironi Manuela

Abstract excerpt

BACKGROUND AND AIMS: ABO encodes a glycosyltranferase which determines the major human histo-blood group. The FUT2 fucosyltransferase allows expression of ABO antigens on the gastrointestinal mucosa and in bodily secretions (secretor phenotype). A nonsense allele in FUT2 represents a susceptibility variant for Crohn's disease, and both the secretor and ABO blood group status affect the composition of the gut...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24268527
DOI: 10.1016/j.crohns.2013.10.014

Genes

ABO
FUT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior.PMID 24268527Read ↗

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