Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Development of 3D Primary Co-Culture Models of the Human Airway

23 May 2025

Abstract excerpt

Current animal and in vitro cell culture models do not fully recapitulate the physiological and pathophysiological characteristics of the human lung. As a result, the translation of these models to clinical practice is very limited, and clinical trials initiated on the extrapolation of such data fail. Although current models are beneficial in fundamental research, there is a need to constantly improve models to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Cancer Cells and Metastasis
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40507840
DOI: 10.3390/ijms26115027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Development of 3D Primary Co-Culture Models of the Human AirwayPMID 40507840Read ↗

Cells and Culture Systems Used to Model the Small Airway Epithelium.Semantic proximity Read ↗

Engineering a 3D Lung Co-culture Platform to Model Epithelial–Fibroblast Interactions in Pulmonary FibrosisSemantic proximity Read ↗

Isolating Bronchial Epithelial Cells from Resected Lung Tissue for Biobanking and Establishing Well-Differentiated Air-Liquid Interface CulturesSemantic proximity Read ↗

In Vitro Modeling of Idiopathic Pulmonary Fibrosis: Lung-on-a-Chip Systems and Other 3D CulturesSemantic proximity Read ↗

Optimization of Normal Human Bronchial Epithelial (NHBE) Cell 3D Cultures for in vitro Lung Model StudiesSemantic proximity Read ↗

Standardized pipeline for establishing, expanding, and differentiating airway and alveolar organoids from human BAL fluidSemantic proximity Read ↗

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epitheliaSemantic proximity Read ↗

Airway and alveolar epithelial cells in cultureSemantic proximity Read ↗

Development of a Novel Air-Liquid Interface Airway Tissue Equivalent Model for In Vitro Respiratory Modeling StudiesSemantic proximity Read ↗

Cell Culture Differentiation and Proliferation Conditions Influence the In Vitro Regeneration of the Human Airway EpitheliumSemantic proximity Read ↗

Transcriptomic Analysis of Air–Liquid Interface Culture in Human Lung Organoids Reveals Regulators of Epithelial DifferentiationSemantic proximity Read ↗

Cell culture differentiation and proliferation conditions influence the <i>in vitro</i> regeneration of the human airway epitheliumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.