Article

Developing a 3D model of the airways

2019-01-01

Abstract excerpt

Chronic cigarette smoke exposure leads to chronic obstructive pulmonary disease (COPD) in susceptible individuals where goblet cell metaplasia, ciliated cell hypoplasia and extra cellular matrix (ECM) thickening are observed. Current in vitro COPD models such as air-liquid interface (ALI) cultures, cannot model the complex morphology and the cell-ECM interaction seen in vivo. No organoid models of COPD currently e...

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Literature Corpus work: 288b32fc-fd0a-5db3-9a96-7170c9ef3f0a
DOI: 10.25560/87742

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