Article
Genetic divergence between the Wistar-Kyoto rat and the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979) - 1 May 1992
Johnson M L, Ely D L, Turner M E
Abstract excerpt
A method of restriction fragment length polymorphism (RFLP) analysis was used to estimate the amount of genetic divergence between the spontaneously hypertensive rat (SHR) strain and the Wistar-Kyoto (WKY) strain. DNA from each strain was digested with eight restriction endonucleases and hybridized with six single copy gene sequences. The number of hybridization bands in each digestion was used to estimate the...
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