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Article

A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity.

Immunity - 22 Jul 2011

Haribhai Dipica, Williams Jason B, Jia Shuang, Nickerson Derek, Schmitt Erica G, Edwards Brandon, Ziegelbauer Jennifer, Yassai Maryam, Li Shun-Hwa, Relland Lance M, Wise Petra M, Chen Andrew, Zheng Yu-Qian, Simpson Pippa M, Gorski Jack, Salzman Nita H, Hessner Martin J, Chatila Talal A, Williams Calvin B

Abstract excerpt

Although both natural and induced regulatory T (nTreg and iTreg) cells can enforce tolerance, the mechanisms underlying their synergistic actions have not been established. We examined the functions of nTreg and iTreg cells by adoptive transfer immunotherapy of newborn Foxp3-deficient mice. As mo...

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Source

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Identifiers

PMID: 21723159
DOI: 10.1016/j.immuni.2011.03.029
PMCID: PMC3295638

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21723159-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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