Article
Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population.
Obesity (Silver Spring, Md.) - 1 Feb 2012
Rouskas Konstantinos, Kouvatsi Anastasia, Paletas Konstantinos, Papazoglou Dimitrios, Tsapas Apostolos, Lobbens Stéphane, Vatin Vincent, Durand Emmanuelle, Labrune Yann, Delplanque Jérôme, Meyre David, Froguel Philippe
Abstract excerpt
Twenty-four single-nucleotide polymorphisms (SNPs) have been reproducibly associated with obesity. We performed a follow-up study for obesity in the Greek adult population. A total of 510 obese and 469 lean adults were genotyped for 24 SNPs. We tested the association with obesity status using logistic regression and we evaluated the combined genetic risk of 24 SNPs by calculating the area under the...
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