Article
Influence of FTO variants on obesity, inflammation and cardiovascular disease risk biomarkers in Spanish children: a case-control multicentre study.
BMC medical genetics - 1 Dec 2013
Olza Josune, Ruperez Azahara I, Gil-Campos Mercedes, Leis Rosaura, Fernandez-Orth Dietmar, Tojo Rafael, Cañete Ramon, Gil Angel, Aguilera Concepcion M
Abstract excerpt
BACKGROUND: Variants in the FTO gene have been associated with obesity in children, but this association has not been shown with other biomarkers. We assessed the association of 52 FTO polymorphisms, spanning the whole gene, with obesity and estimated the influence of these polymorphisms on anthropometric, clinical and metabolic parameters as well as inflammation and cardiovascular disease (CVD) risk biomarkers...
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