Article
The combined effect of MC4R and FTO risk alleles on childhood obesity in Greece.
Hormones (Athens, Greece) - 1 Jan 2000
Lazopoulou Natalia, Gkioka Eleana, Ntalla Ioanna, Pervanidou Panagiota, Magiakou Alexandra-Maria, Roma-Giannikou Eleftheria, Chrousos George P, Papassotiriou Ioannis, Dedoussis George, Kanaka-Gantenbein Christina
Abstract excerpt
OBJECTIVE: Single nucleotide polymorphism (SNP) risk alleles of obesogenic genes, such as the fat mass and obesity-associated protein (FTO) and the melanocortin-4 receptor (MC4R) gene, have been described in both paediatrics and adult populations. The aim of this study was to investigate the combined effect of FTO and MC4R risk alleles on the obese phenotype and metabolic profile of young children and adolescents...
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