Article
Analysis of the Impact of Common Polymorphisms of the FTO and MC4R Genes with the Risk of Severe Obesity in Saudi Arabian Population.
Genetic testing and molecular biomarkers - 1 Mar 2018
Cyrus Cyril, Ismail Mona H, Chathoth Shahanas, Vatte Chittibabu, Hasen Majd, Al Ali Amein
Abstract excerpt
BACKGROUND: Obesity has reached epidemic proportions worldwide resulting in a serious public health problem. In Saudi Arabia, 28.7% of the population is obese due largely to the adoption of western dietary patterns over the last decade. The fat-mass and obesity associated (FTO) and melanocortin-4 receptor (MC4R) genes are ubiquitously expressed in the brain and pancreatic islets, and are the main link between the...
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