Article
Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.
Diabetes - 1 Aug 2008
Chang Yi-Cheng, Liu Pi-Hua, Lee Wei-Jei, Chang Tien-Jyun, Jiang Yi-Der, Li Hung-Yuan, Kuo Shan-Shan, Lee Kuang-Chin, Chuang Lee-Ming
Abstract excerpt
OBJECTIVE: Genetic variants in the fat mass and obesity-associated (FTO) gene have been linked with obesity and type 2 diabetes in European populations. We aimed to test the role of FTO genetic variants in obesity and type 2 diabetes in the Chinese population. RESEARCH DESIGN AND METHODS: We genotyped 19 single-nucleotide polymorphisms (SNPs) spanning from the 3' end of the neighboring RPGRIP1L gene to the 5'...
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