Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated genomic analyses of ovarian carcinoma.

Nature - 29 Jun 2011

Abstract excerpt

A catalogue of molecular aberrations that cause ovarian cancer is critical for developing and deploying therapies that will improve patients' lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade serous ovarian adenocarcinomas and the DNA sequences of exons from coding genes in 316 of these tumours. Here we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma
Share to DNA Methylation
Share to Gene Dosage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Neoplastic

Share to Genomics

Share to MicroRNAs

Share to Ovarian Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 21720365
DOI: 10.1038/nature10166
PMCID: PMC3163504

Genes

BRCA1
BRCA2
CCNE1
CDK12
FOXM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated genomic analyses of ovarian carcinoma.PMID 21720365Read ↗

Genomic Landscapes of Endometrioid and Mucinous Ovarian Cancers and Morphologically Similar Tumor Types.Semantic proximity Read ↗

Genome Wide DNA Copy Number Analysis of Serous Type Ovarian Carcinomas Identifies Genetic Markers Predictive of Clinical OutcomeSemantic proximity Read ↗

Critical molecular abnormalities in high-grade serous carcinoma of the ovary.Semantic proximity Read ↗

High-Grade Serous Ovarian Carcinoma in the Genomics Era: Current Applications, Challenges and Future Directions.Semantic proximity Read ↗

Genomic Analyses of Germline and Somatic Variation in High-Grade Serous Ovarian CancerSemantic proximity Read ↗

The Changing View of High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Genetic and molecular changes in ovarian cancerSemantic proximity Read ↗

The Molecular Landscape of Ovarian Neoplasms: A Review.Semantic proximity Read ↗

Genomic instability and CCNE1 amplification as emerging biomarkers for stratifying high-grade serous ovarian cancerSemantic proximity Read ↗

Multiomic characterisation of high grade serous ovarian carcinoma enables high resolution patient stratificationSemantic proximity Read ↗

Genomic analyses of germline and somatic variation in high-grade serous ovarian cancerSemantic proximity Read ↗

Integrated genomic characterization of endometrial carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.