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Article

Critical molecular abnormalities in high-grade serous carcinoma of the ovary.

Expert reviews in molecular medicine - 1 Aug 2008

Köbel Martin, Huntsman David, Gilks C Blake

Abstract excerpt

Ovarian carcinomas show more morphological heterogeneity than adenocarcinomas of any other body site. It has recently become clear that the morphologically defined subtypes of ovarian carcinoma are distinct diseases, with different risk factors, molecular events during oncogenesis, likelihood of spread, responses to chemotherapy, and outcomes. This review focuses on molecular abnormalities (in genes expressing...

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Identifiers

PMID: 18671886
DOI: 10.1017/S146239940800077X

Genes

BRCA1
CCND1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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