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Article

The Molecular Landscape of Ovarian Neoplasms: A Review.

Surgical pathology clinics - 1 Jun 2026

Momeni-Boroujeni Amir, Murali Rajmohan

Abstract excerpt

This article summarizes the molecular landscape of epithelial and non-epithelial ovarian tumors, integrating current genomic and immunophenotypic data. High-grade serous carcinomas are defined by TP53 and homologous recombination defects, while low-grade serous, mucinous, endometrioid, and clear cell carcinomas exhibit pathway-specific mutations such as MAPK/MEK and PI3K/AKT pathway alterations. Sex cord-stromal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42091279
DOI: 10.1016/j.path.2026.01.006

Genes

DICER1
BRCA1
CTNNB1
FOXL2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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