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Article

Genomic Landscapes of Endometrioid and Mucinous Ovarian Cancers and Morphologically Similar Tumor Types.

Cancer research communications - 1 Nov 2025

Hallberg Dorothy, Eastman Alice C, Koul Shashikant, Bruhm Daniel C, Papp Eniko, Davenport Simon, Adleff Vilmos, Ferreira Leonardo, Niknafs Noushin, Medina Jamie E, Cristiano Stephen, Hruban Carolyn, Fiksel Jacob, Lebarbenchon Kaui P, Aparicio Luis, Vulpescu Nicholas A, Kuo Kuan-Ting, Ahuja Nita, Drapkin Ronny, Jung Euihye, Kim Sarah H, Eckert Mark A, Lengyel Ernst, Nakayama Kentaro, Ayhan Ayse, Shih Ie-Ming, Wang Tian-Li, Lavie Ofer, Rennert Gad, Easwaran Hariharan, Baylin Stephen B, Press Michael F, Velculescu Victor E, Scharpf Robert B

Abstract excerpt

Endometrioid and mucinous ovarian carcinomas represent nearly a fifth of ovarian cancers, but their molecular characteristics and pathologic origins are poorly understood. To identify the genomic and epigenomic alterations characteristic of these ovarian cancer subtypes and evaluate links to morphologically similar tumors from other sites, we performed a combination of sequence, copy number, mutation signature,...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40981433
DOI: 10.1158/2767-9764.CRC-25-0147
PMCID: PMC12586982

Genes

NF1
ESR1
JAK1
MED1
NF2
NOTCH4
PTEN
RAD51C
SMARCA1
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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