Article
New words in human mutagenesis.
BMC bioinformatics - 30 Jun 2011
Panchin Alexander Y, Mitrofanov Sergey I, Alexeevski Andrei V, Spirin Sergey A, Panchin Yuri V
Abstract excerpt
BACKGROUND: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C > T) mutations in CpG (CG) dinucleotides. The molecular mechanisms underlying this bias are important factors in human genome evolution and cancer development. The discovery of other nucleotide contexts that have profound effects on...
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