Article

Sequence effects on mutation rates investigated in whole-genome sequenced UK Biobank participants

2026-03-07

Abstract excerpt

UK Biobank has released whole genome sequence data for 500,000 participants, including allele counts for hundreds of millions of variants and these were considered in the context of the pentanucleotide background on which they occurred. Variants with an allele count of 25 were found to closely mirror previously reported de novo mutations (DNMs) in terms of the frequencies of variant types. Therefore these variants...

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Identifiers and source

Literature Corpus work: 899f5347-5584-51a7-927e-a22f4ac2c149
DOI: 10.64898/2026.03.06.710079

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