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Article

Context dependent substitution biases vary within the human genome.

BMC bioinformatics - 15 Sept 2010

Nevarez P Andrew, DeBoever Christopher M, Freeland Benjamin J, Quitt Marissa A, Bush Eliot C

Abstract excerpt

BACKGROUND: Models of sequence evolution typically assume that different nucleotide positions evolve independently. This assumption is widely appreciated to be an over-simplification. The best known violations involve biases due to adjacent nucleotides. There have also been suggestions that biases exist at larger scales, however this possibility has not been systematically explored. RESULTS: To address this we...

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Identifiers

PMID: 20843365
DOI: 10.1186/1471-2105-11-462
PMCID: PMC2945941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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