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Article

Cryptic variation in the human mutation rate.

PLoS biology - 3 Feb 2009

Hodgkinson Alan, Ladoukakis Emmanuel, Eyre-Walker Adam

Abstract excerpt

The mutation rate is known to vary between adjacent sites within the human genome as a consequence of context, the most well-studied example being the influence of CpG dinucelotides. We investigated whether there is additional variation by testing whether there is an excess of sites at which both humans and chimpanzees have a single-nucleotide polymorphism (SNP). We found a highly significant excess of such...

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Identifiers

PMID: 19192947
DOI: 10.1371/journal.pbio.1000027
PMCID: PMC2634788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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