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Article

Mutational spectrum in the recent human genome inferred by single nucleotide polymorphisms.

Genomics - 1 Nov 2006

Jiang Cizhong, Zhao Zhongming

Abstract excerpt

So far, there is no genome-wide estimation of the mutational spectrum in humans. In this study, we systematically examined the directionality of the point mutations and maintenance of GC content in the human genome using approximately 1.8 million high-quality human single nucleotide polymorphisms and their ancestral sequences in chimpanzees. The frequency of C-->T (G-->A) changes was the highest among all...

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PMID: 16860534
DOI: 10.1016/j.ygeno.2006.06.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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