Article
Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria.
Cell - 2 Nov 1990
Hulton C S, Seirafi A, Hinton J C, Sidebotham J M, Waddell L, Pavitt G D, Owen-Hughes T, Spassky A, Buc H, Higgins C F
Abstract excerpt
Changes in DNA supercoiling in response to environmental signals such as osmolarity, temperature, or anaerobicity appear to play an underlying role in the regulation of gene expression in bacteria. Extensive genetic analyses have implicated the osmZ gene in this regulatory process: osmZ mutations...
Topics
- Bacterial Proteins
- Base Sequence
- Blotting, Southern
- DNA Transposable Elements
- DNA, Bacterial
- DNA, Superhelical
- DNA-Binding Proteins
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genotype
- Molecular Sequence Data
- Mutagenesis, Insertional
- Oligonucleotide Probes