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Article

Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria.

Cell - 2 Nov 1990

Hulton C S, Seirafi A, Hinton J C, Sidebotham J M, Waddell L, Pavitt G D, Owen-Hughes T, Spassky A, Buc H, Higgins C F

Abstract excerpt

Changes in DNA supercoiling in response to environmental signals such as osmolarity, temperature, or anaerobicity appear to play an underlying role in the regulation of gene expression in bacteria. Extensive genetic analyses have implicated the osmZ gene in this regulatory process: osmZ mutations are highly pleiotropic and alter the topology of cellular DNA. We have shown that the product of the osmZ gene is the...

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Identifiers

PMID: 2171779
DOI: 10.1016/0092-8674(90)90458-q

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria.PMID 2171779Read ↗

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