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Article

Paired-end RAD-seq for de novo assembly and marker design without available reference.

Bioinformatics (Oxford, England) - 15 Aug 2011

Willing Eva-Maria, Hoffmann Margarete, Klein Juliane D, Weigel Detlef, Dreyer Christine

Abstract excerpt

MOTIVATION: Next-generation sequencing technologies have facilitated the study of organisms on a genome-wide scale. A recent method called restriction site associated DNA sequencing (RAD-seq) allows to sample sequence information at reduced complexity across a target genome using the Illumina platform. Single-end RAD-seq has proven to provide a large number of informative genetic markers in reference as well as...

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PMID: 21712251
DOI: 10.1093/bioinformatics/btr346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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