Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C.

doi:10.1016/j.jhep.2011.03.015

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C.

Journal of hepatology - 1 Dec 2011

Tillmann Hans L, Patel Keyur, Muir Andrew J, Guy Cynthia D, Li Josephine H, Lao Xiang Qian, Thompson Alexander, Clark Paul J, Gardner Stephen D, McHutchison John G, McCarthy Jeanette J

Abstract excerpt

BACKGROUND & AIMS: IL28B polymorphisms have been associated with both treatment induced and spontaneous clearance of hepatitis C virus (HCV). We previously found that LDL cholesterol levels were higher in chronic hepatitis C (CHC) patients with the CC genotype at the rs12979860 polymorphism, located proximal to the IL28 gene. Here we analyzed the association of steatosis with IL28B genotype in treatment naïve...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Liver

Share to Hepatitis C, Chronic

Share to Interferons

Share to Interleukins

Share to Lipid Metabolism

Share to Lipoproteins

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 21703198
DOI: 10.1016/j.jhep.2011.03.015
PMCID: PMC3763913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beneficial IL28B genotype associated with lower frequency of hepatic steatosis in patients with chronic hepatitis C.PMID 21703198Read ↗

The association of IL28B genotype with the histological features of chronic hepatitis C is HCV genotype dependent.Semantic proximity Read ↗

Effects of IL28B rs12979860 CC genotype on metabolic profile and sustained virologic response in patients with genotype 1 chronic hepatitis C.Semantic proximity Read ↗

Interleukin-28B rs12979860 C allele: Protective against advanced fibrosis in chronic hepatitis C genotype 1 infection.Semantic proximity Read ↗

Impact of IL28B genetic variation on HCV-induced liver fibrosis, inflammation, and steatosis: a meta-analysis.Semantic proximity Read ↗

IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.Semantic proximity Read ↗

Prevalence and clinical implications of IL28B genotypes in Taiwanese patients with chronic hepatitis C.Semantic proximity Read ↗

Genetics of IL28B and HCV--response to infection and treatment.Semantic proximity Read ↗

Interleukin-28B TT genotype is frequently found in patients with hepatitis C virus cirrhosis but does not influence hepatocarcinogenesis.Semantic proximity Read ↗

Interleukin 28B polymorphisms are the only common genetic variants associated with low-density lipoprotein cholesterol (LDL-C) in genotype-1 chronic hepatitis C and determine the association between LDL-C and treatment response.Semantic proximity Read ↗

Impact of IL28B-related single nucleotide polymorphisms on liver histopathology in chronic hepatitis C genotype 2 and 3.Semantic proximity Read ↗

The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection.Semantic proximity Read ↗

IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.