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Article

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1

24 Jun 2011

Abstract excerpt

Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumours were recently identified as an additional subgroup, characterised as oestrogen receptor negative and androgen receptor positive (ER− AR+), but with an expression profile resembling ER+ luminal breast cancer. One possible explanation for the apparent incongruity is...

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PMID: 21701558
DOI: 10.1038/emboj.2011.216

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