Article
Identification of molecular apocrine breast tumours by microarray analysis.
Oncogene - 7 Jul 2005
Farmer Pierre, Bonnefoi Herve, Becette Veronique, Tubiana-Hulin Michele, Fumoleau Pierre, Larsimont Denis, Macgrogan Gaetan, Bergh Jonas, Cameron David, Goldstein Darlene, Duss Stephan, Nicoulaz Anne-Laure, Brisken Cathrin, Fiche Maryse, Delorenzi Mauro, Iggo Richard
Abstract excerpt
Previous microarray studies on breast cancer identified multiple tumour classes, of which the most prominent, named luminal and basal, differ in expression of the oestrogen receptor alpha gene (ER). We report here the identification of a group of breast tumours with increased androgen signalling and a 'molecular apocrine' gene expression profile. Tumour samples from 49 patients with large operable or locally...
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