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Article

Prognostic value of androgen receptor and FOXA1 co-expression in non-metastatic triple negative breast cancer and correlation with other biomarkers.

British journal of cancer - 1 Jul 2018

Guiu Séverine, Mollevi Caroline, Charon-Barra Céline, Boissière Florence, Crapez Evelyne, Chartron Elodie, Lamy Pierre-Jean, Gutowski Marian, Bourgier Céline, Romieu Gilles, Simony-Lafontaine Joelle, Jacot William

Abstract excerpt

BACKGROUND: In luminal androgen receptor (AR) tumours, FOXA1 may direct AR to sites occupied by ER in luminal tumours, thus stimulating proliferation. METHODS: AR and FOXA1 expression were evaluated by immunohistochemistry in 333 non-metastatic triple-negative breast cancers (TNBC). Positivity threshold was set at ≥ 1% staining. Lymphocytic infiltration, PD-L1expression, PIK3CA mutations, PTEN defects and BRCA1...

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Share to B7-H1 Antigen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Class I Phosphatidylinositol 3-Kinases

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Share to Hepatocyte Nuclear Factor 3-alpha

Share to Neoplasm Recurrence, Local

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Source

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Identifiers

PMID: 29880907
DOI: 10.1038/s41416-018-0142-6
PMCID: PMC6035246

Genes

FOXA1
BRCA1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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