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Polymorphisms and haplotypes in caspases 8 and 9 genes and risk for prostate cancer: a case-control study in cohort of North India.

Urologic oncology - 1 Jan 2000

George Ginu P, Mandal Raju K, Kesarwani Pravin, Sankhwar Satya N, Mandhani Anil, Mittal Rama D

Abstract excerpt

OBJECTIVE: Despite the potential importance of apoptosis pathways in prostate tumor etiology, little has been published regarding prostate tumor risk associated with common gene variants in caspases (CASP). Normal variations within the sequence of apoptotic genes may lead to suboptimal apoptotic capacity and therefore increased cancer risk. MATERIALS AND METHODS: Using data from a hospital-based case-control...

Topics

Aged
Apoptosis
Biomarkers, Tumor
Case-Control Studies
Caspase 8
Caspase 9
Cohort Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Prostatic Neoplasms

Risk Factors

Source

Identifiers

PMID: 21396853
DOI: 10.1016/j.urolonc.2010.08.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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