Article
Death receptor 4 variants enhanced prostate cancer risk in North Indian population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2015
Mittal Rama D, Mandal Raju K, Singh Abhinav, Srivastava Priyanka
Abstract excerpt
Death receptor 4 (DR4) is a tumor suppressor gene and plays an important mediator of apoptosis. Polymorphism in DR4 gene may reduce apoptotic capacity and provoke proliferation of cell and cancer. We evaluated genetic polymorphisms of DR4 gene in association with risk of prostate cancer (PCa) in Northern Indian population. We have recruited 192 PCa patients and 225 cancer-free ages matched unrelated healthy...
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