Article
Caspase 9 and caspase 8 gene polymorphisms and susceptibility to bladder cancer in north Indian population.
Annals of surgical oncology - 1 Jul 2009
Gangwar Ruchika, Mandhani Anil, Mittal Rama Devi
Abstract excerpt
BACKGROUND: Dysregulation of apoptosis plays a crucial role in carcinogenesis. Our aim was to investigate the association of Caspase 9 and Caspase 8 gene polymorphism with bladder cancer (BC) susceptibility. METHODS: We undertook a case-control study of 212 (BC) cases and 250 controls to investigate the association between Caspase 9-1263A > G, Caspase 9-293del, and Caspase 8-6 N ins/del polymorphism and BC...
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