A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus.

doi:10.1016/0092-8674(90)90289-q

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Article

A single amino acid substitution within the matrix protein of a type D retrovirus converts its morphogenesis to that of a type C retrovirus.

Cell - 5 Oct 1990

Rhee S S, Hunter E

Abstract excerpt

Two different morphogenic processes of retroviral capsid assembly have been observed: the capsid is either assembled at the plasma membrane during the budding process (type C), or preassembled within the cytoplasm (types B and D). We describe here a gag mutant of Mason-Pfizer monkey virus, a type...

Topics

Amino Acid Sequence
Animals
Betaretrovirus
Capsid
Cell Line
Clone Cells
Gene Products, gag
HeLa Cells
Molecular Sequence Data
Morphogenesis
Mutation
Retroviridae
Sequence Homology, Nucleic Acid
Transfection
Viral Matrix Proteins
Virion

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