Article
Separate assembly and transport domains within the Gag precursor of Mason-Pfizer monkey virus.
Journal of virology - 1 Oct 1999
Sakalian M, Hunter E
Abstract excerpt
Mason-Pfizer monkey virus (M-PMV), the prototypical type D retrovirus, assembles immature capsids within the cytoplasm of the cell prior to plasma membrane interaction. Several mutants of M-PMV Gag have been described which display altered transport, assembly, or both. In this report, we describe the use of an in vitro synthesis and assembly system to distinguish between defects in intracellular transport and the...
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