Article
Preassembled capsids of type D retroviruses contain a signal sufficient for targeting specifically to the plasma membrane.
Journal of virology - 1 Aug 1990
Rhee S S, Hui H X, Hunter E
Abstract excerpt
The capsids of Mason-Pfizer monkey virus (M-PMV), an immunosuppressive type D retrovirus, are preassembled in the infected cell cytoplasm and are then transported to the plasma membrane, where they are enveloped in a virus glycoprotein-containing lipid bilayer. The role of viral glycoprotein in intracellular transport of M-PMV capsids was investigated with a spontaneous mutant (5A) of M-PMV, which we show here to...
Topics
- Animals
- Base Sequence
- Capsid
- Cell Line
- Cell Membrane
- Cloning, Molecular
- DNA, Viral
- Genes, Viral
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
