Article
Measles virus nucleocapsid transport to the plasma membrane requires stable expression and surface accumulation of the viral matrix protein.
Cellular microbiology - 1 May 2007
Runkler Nicole, Pohl Christine, Schneider-Schaulies Sibylle, Klenk Hans-Dieter, Maisner Andrea
Abstract excerpt
In measles virus (MV)-infected cells the matrix (M) protein plays a key role in virus assembly and budding processes at the plasma membrane because it mediates the contact between the viral surface glycoproteins and the nucleocapsids. By exchanging valine 101, a highly conserved residue among all paramyxoviral M proteins, we generated a recombinant MV (rMV) from cloned cDNA encoding for a M protein with an...
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