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Article

Drosophila nucleoporin Nup154 controls cell viability, proliferation and nuclear accumulation of Mad transcription factor.

Tissue & cell - 1 Aug 2011

Colozza Gabriele, Montembault Emilie, Quénerch'du Emilie, Riparbelli Maria Giovanna, D'Avino Pier Paolo, Callaini Giuliano

Abstract excerpt

Nuclear Pore Complexes (NPCs) are involved in the regulation of nucleo-cytoplasmic trafficking. Drosophila Nup154 encodes a nucleoporin component of the NPC that is expressed in high proliferating tissues such as germ cells. Hypomorphic mutations in this gene cause male and female sterility and reduction of cell proliferation in the adult fly. Here, we present evidences of a decrease in the number of...

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Identifiers

PMID: 21696798
DOI: 10.1016/j.tice.2011.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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