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Article

Synergistic actions of Nup43 and Myosin VI drive actin cone assembly during Drosophila spermiogenesis.

Genetics - 2 Sept 2026

Kawadkar Jyotsna, Hermon Ashley Suraj, Kumar Rohit, Mishra Ram Kumar

Abstract excerpt

Nuclear pore complexes, composed of nucleoporins (Nups), are critical for bidirectional nucleocytoplasmic transport and regulate various cellular processes, thus contributing significantly to organismal development. Intriguingly, the integral Nup107 complex member, Nup43, is linked with premature ovarian insufficiency. Here, we report that Nup43 plays essential roles in Drosophila fertility, and Nup43 null mutant...

Read the complete abstract on PubMed

Topics

Animals
Spermatogenesis
Male
Nuclear Pore Complex Proteins
Female
Drosophila Proteins
Actins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Myosin Heavy Chains

Fertility

Drosophila melanogaster

Drosophila

Mutation

Source

Identifiers

PMID: 42374827
DOI: 10.1093/genetics/iyag164

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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